Modeling the human brain in organoids

ForInter scientists are researching the interactions of cells in the human brain using a three-dimensional living tissue structure. Bavarian scientists from the fields of stem cell biology, biochemistry and molecular neuropathology, bioinformatics, neuropathology and ethics and law are working synergistically on the decoding of cell-cell interactions of human brain cells and their normative significance in the development of brain diseases.

ForInter describes a highly innovative approach for the first time in Bavaria, in which cell-cell interactions of different human brain cells as well as new genome editing approaches and single cell analyses are the scientific focus. For the first time, the network is creating a platform to analyze the function of the brain, to study different human brain cells in direct interaction on a cell biological and molecular level and at the same time to prospectively investigate the legal and ethical implications of therapies based on this. The Ministry of Science and the Arts is funding the network with 4 million euros over a period of four years.