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Links to Publications 2022

Publications 2022

1.

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus.

Mackensen A, Müller F, Mougiakakos D, Böltz S, Wilhelm A, Aigner M, Völkl S, Simon D, Kleyer A, Munoz L, Kretschmann S, Kharboutli S, Gary R, Reimann H, Rösler W, Uderhardt S, Bang H, Herrmann M, Ekici AB, Buettner C, Habenicht KM, Winkler TH, Krönke G, Schett G.

Nat Med. 2022 Oct;28(10):2124-2132. doi: 10.1038/s41591-022-02017-5. Epub 2022 Sep 15.

PMID: 36109639

2.

Targeting cytokines in inflammatory bowel disease.

Neurath MF.

Sci Transl Med. 2022 Dec 14;14(675):eabq4473. doi: 10.1126/scitranslmed.abq4473. Epub 2022 Dec 14.

PMID: 36516267 Review.

3.

Immune response in COVID-19: what is next?

Li Q, Wang Y, Sun Q, Knopf J, Herrmann M, Lin L, Jiang J, Shao C, Li P, He X, Hua F, Niu Z, Ma C, Zhu Y, Ippolito G, Piacentini M, Estaquier J, Melino S, Weiss FD, Andreano E, Latz E, Schultze JL, Rappuoli R, Mantovani A, Mak TW, Melino G, Shi Y.

Cell Death Differ. 2022 Jun;29(6):1107-1122. doi: 10.1038/s41418-022-01015-x. Epub 2022 May 17.

PMID: 35581387 Free PMC article. Review.

4.

Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration.

Silvin A, Uderhardt S, Piot C, Da Mesquita S, Yang K, Geirsdottir L, Mulder K, Eyal D, Liu Z, Bridlance C, Thion MS, Zhang XM, Kong WT, Deloger M, Fontes V, Weiner A, Ee R, Dress R, Hang JW, Balachander A, Chakarov S, Malleret B, Dunsmore G, Cexus O, Chen J, Garel S, Dutertre CA, Amit I, Kipnis J, Ginhoux F.

Immunity. 2022 Aug 9;55(8):1448-1465.e6. doi: 10.1016/j.immuni.2022.07.004. Epub 2022 Aug 4.

PMID: 35931085

5.

Psoriatic arthritis from a mechanistic perspective.

Schett G, Rahman P, Ritchlin C, McInnes IB, Elewaut D, Scher JU.

Nat Rev Rheumatol. 2022 Jun;18(6):311-325. doi: 10.1038/s41584-022-00776-6. Epub 2022 May 5.

PMID: 35513599 Review.

6.

Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.

Denk D, Petrocelli V, Conche C, Drachsler M, Ziegler PK, Braun A, Kress A, Nicolas AM, Mohs K, Becker C, Neurath MF, Farin HF, Buchholz CJ, Andreux PA, Rinsch C, Greten FR.

Immunity. 2022 Nov 8;55(11):2059-2073.e8. doi: 10.1016/j.immuni.2022.09.014. Epub 2022 Oct 19.

PMID: 36351375

7.

Editorial overview: Osteoimmunology.

Schett G, Takayanagi H.

Bone. 2022 Sep;162:116466. doi: 10.1016/j.bone.2022.116466. Epub 2022 Jun 8.

PMID: 35688362 No abstract available.

8.

Organoids in gastrointestinal diseases: from experimental models to clinical translation.

Günther C, Winner B, Neurath MF, Stappenbeck TS.

Gut. 2022 Sep;71(9):1892-1908. doi: 10.1136/gutjnl-2021-326560. Epub 2022 May 30.

PMID: 35636923 Free PMC article. Review.

9.

Reply.

Schett G, Simon D, Fagni F, Tascilar K.

Arthritis Rheumatol. 2022 Dec;74(12):2043. doi: 10.1002/art.42305. Epub 2022 Oct 21.

PMID: 35819811 Free PMC article. No abstract available.

10.

Reply.

Simon D, Fagni F, Tascilar K, Schett G.

Arthritis Rheumatol. 2022 May;74(5):909-910. doi: 10.1002/art.42012. Epub 2022 Mar 20.

PMID: 34725969 Free PMC article. No abstract available.

11.

Role of CAR T Cell Metabolism for Therapeutic Efficacy.

Rial Saborido J, Völkl S, Aigner M, Mackensen A, Mougiakakos D.

Cancers (Basel). 2022 Nov 4;14(21):5442. doi: 10.3390/cancers14215442.

PMID: 36358860 Free PMC article. Review.

12.

Autoantibodies in Rheumatoid Arthritis: Historical Background and Novel Findings.

Sokolova MV, Schett G, Steffen U.

Clin Rev Allergy Immunol. 2022 Oct;63(2):138-151. doi: 10.1007/s12016-021-08890-1. Epub 2021 Sep 8.

PMID: 34495490 Free PMC article. Review.

13.

No NETs no TIME: Crosstalk between neutrophil extracellular traps and the tumor immune microenvironment.

Fang Q, Stehr AM, Naschberger E, Knopf J, Herrmann M, Stürzl M.

Front Immunol. 2022 Dec 23;13:1075260. doi: 10.3389/fimmu.2022.1075260. eCollection 2022.

PMID: 36618417 Free PMC article. Review.

14.

Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.

Leppkes M, Lindemann A, Gößwein S, Paulus S, Roth D, Hartung A, Liebing E, Zundler S, Gonzalez-Acera M, Patankar JV, Mascia F, Scheibe K, Hoffmann M, Uderhardt S, Schauer C, Foersch S, Neufert C, Vieth M, Schett G, Atreya R, Kühl AA, Bleich A, Becker C, Herrmann M, Neurath MF.

Gut. 2022 Dec;71(12):2414-2429. doi: 10.1136/gutjnl-2021-324725. Epub 2021 Dec 3.

PMID: 34862250 Free PMC article.

15.

Wahrnehmung der Corona-Pandemie durch Neurodermitispatienten - Ergebnisse aus dem Neurodermitisregister TREATgermany.

Helmert C, Siegels D, Haufe E, Abraham S, Heratizadeh A, Kleinheinz A, Harder I, Schäkel K, Effendy I, Wollenberg A, Sticherling M, Stahl M, Worm M, Schwichtenberg U, Schwarz B, Rossbacher J, Buck PM, Schenck F, Werfel T, Weidinger S, Schmitt J; das TREATgermany Studienteam.

J Dtsch Dermatol Ges. 2022 Jan;20(1):45-58. doi: 10.1111/ddg.14655_g.

PMID: 35040570 German.

16.

Drei Generationen Leiden: Cryopyrin-assoziiertes periodisches Syndrom mit familiärer NLRP3-Mutation.

Wagner N, Manger B, Kittler J, Rech J, Sticherling M, Berking C, Kirchberger MC.

J Dtsch Dermatol Ges. 2022 Jan;20(1):106-111. doi: 10.1111/ddg.14650_g.

PMID: 35040579 German. No abstract available.

17.

Neutrophil extracellular traps drive epithelial-mesenchymal transition of human colon cancer.

Stehr AM, Wang G, Demmler R, Stemmler MP, Krug J, Tripal P, Schmid B, Geppert CI, Hartmann A, Muñoz LE, Schoen J, Völkl S, Merkel S, Becker C, Schett G, Grützmann R, Naschberger E, Herrmann M, Stürzl M.

J Pathol. 2022 Apr;256(4):455-467. doi: 10.1002/path.5860. Epub 2022 Feb 15.

PMID: 34939675

18.

Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease.

Mellor LF, Gago-Lopez N, Bakiri L, Schmidt FN, Busse B, Rauber S, Jimenez M, Megías D, Oterino-Soto S, Sanchez-Prieto R, Grivennikov S, Pu X, Oxford J, Ramming A, Schett G, Wagner EF.

Ann Rheum Dis. 2022 Jul 4;81(10):1400-8. doi: 10.1136/annrheumdis-2022-222229. Online ahead of print.

PMID: 35788494 Free PMC article.

19.

Response to secukinumab on synovitis using Power Doppler ultrasound in psoriatic arthritis: 12-week results from a phase III study, ULTIMATE.

D'Agostino MA, Schett G, López-Rdz A, Šenolt L, Fazekas K, Burgos-Vargas R, Maldonado-Cocco J, Naredo E, Carron P, Duggan AM, Goyanka P, Boers M, Gaillez C.

Rheumatology (Oxford). 2022 May 5;61(5):1867-1876. doi: 10.1093/rheumatology/keab628.

PMID: 34528079 Free PMC article. Clinical Trial.

20.

Stromal cell regulation of inflammatory responses.

Friščić J, Hoffmann MH.

Curr Opin Immunol. 2022 Feb;74:92-99. doi: 10.1016/j.coi.2021.10.006. Epub 2021 Nov 27.

PMID: 34847474 Review.

21.

Periodontitis-Derived Dark-NETs in Severe Covid-19.

Vitkov L, Knopf J, Krunić J, Schauer C, Schoen J, Minnich B, Hannig M, Herrmann M.

Front Immunol. 2022 Apr 12;13:872695. doi: 10.3389/fimmu.2022.872695. eCollection 2022.

PMID: 35493525 Free PMC article. Review.

22.

Neutrophils' Extracellular Trap Mechanisms: From Physiology to Pathology.

Schoen J, Euler M, Schauer C, Schett G, Herrmann M, Knopf J, Yaykasli KO.

Int J Mol Sci. 2022 Oct 25;23(21):12855. doi: 10.3390/ijms232112855.

PMID: 36361646 Free PMC article. Review.

23.

Formation and Clearance of NETs in Health and Disease.

Knopf J, Mahajan A, Muñoz LE, Herrmann M.

Cells. 2022 Dec 12;11(24):4022. doi: 10.3390/cells11244022.

PMID: 36552786 Free PMC article.

24.

Rear Window-What Can the Gut Tell Us About Long-COVID?

Leppkes M, Neurath MF.

Gastroenterology. 2022 Aug;163(2):376-378. doi: 10.1053/j.gastro.2022.05.044. Epub 2022 Jun 2.

PMID: 35660031 Free PMC article. No abstract available.

25.

The Gut-Immune-Brain Axis: An Important Route for Neuropsychiatric Morbidity in Inflammatory Bowel Disease.

Masanetz RK, Winkler J, Winner B, Günther C, Süß P.

Int J Mol Sci. 2022 Sep 21;23(19):11111. doi: 10.3390/ijms231911111.

PMID: 36232412 Free PMC article. Review.

26.

Cold or hot snare in endoscopy - that is the question.

Vieth M, Neurath MF.

Endosc Int Open. 2022 May 13;10(5):E580-E581. doi: 10.1055/a-1776-7685. eCollection 2022 May.

PMID: 35571466 Free PMC article. No abstract available.

27.

The Role of Programmed Necrosis in Colorectal Cancer.

Yu YQ, Gamez-Belmonte R, Patankar JV, Liebing E, Becker C.

Cancers (Basel). 2022 Sep 1;14(17):4295. doi: 10.3390/cancers14174295.

PMID: 36077828 Free PMC article. Review.

28.

Towards preventive treatment of rheumatoid arthritis.

Rech J, Schett G.

Lancet. 2022 Jul 23;400(10348):253-255. doi: 10.1016/S0140-6736(22)01327-7.

PMID: 35871801 No abstract available.

29.

Deciphering Novel Mechanistic and Pharmacokinetic Effects of Tofacitinib in Intestinal Inflammation: Expect the Unexpected.

Atreya R, Neurath MF.

Cell Mol Gastroenterol Hepatol. 2022;13(2):672-673. doi: 10.1016/j.jcmgh.2021.10.003. Epub 2021 Nov 2.

PMID: 34740616 Free PMC article. No abstract available.

30.

Impact of Epithelial Cell Shedding on Intestinal Homeostasis.

Ngo PA, Neurath MF, López-Posadas R.

Int J Mol Sci. 2022 Apr 9;23(8):4160. doi: 10.3390/ijms23084160.

PMID: 35456978 Free PMC article. Review.

31.

Checkpoint-inhibitor induced Polyserositis with Edema.

Zierold S, Akcetin LS, Gresser E, Maier AM, König A, Kramer R, Theurich S, Tomsitz D, Erdmann M, French LE, Rudelius M, Heinzerling L.

Cancer Immunol Immunother. 2022 Dec;71(12):3087-3092. doi: 10.1007/s00262-022-03211-7. Epub 2022 May 16.

PMID: 35576074 Free PMC article.

32.

Real Life Study of Lenvatinib Therapy for Hepatocellular Carcinoma: RELEVANT Study.

Casadei-Gardini A, Rimini M, Kudo M, Shimose S, Tada T, Suda G, Goh MJ, Jefremow A, Scartozzi M, Cabibbo G, Campani C, Tamburini E, Tovoli F, Ueshima K, Aoki T, Iwamoto H, Torimura T, Kumada T, Hiraoka A, Atsukawa M, Itobayashi E, Toyoda H, Sakamoto N, Sho T, Kang W, Siebler J, Neurath MF, Burgio V, Cascinu S.

Liver Cancer. 2022 Jul 11;11(6):527-539. doi: 10.1159/000525145. eCollection 2022 Dec.

PMID: 36589723 Free PMC article.

33.

Long-term treatment in rheumatoid arthritis: do biological and targeted-synthetic DMARDs increase the risk of malignancy?

Fagni F, Simon D.

Rheumatology (Oxford). 2022 May 5;61(5):1758-1759. doi: 10.1093/rheumatology/keab750.

PMID: 34648000 No abstract available.

34.

Synovial Macrophage and Fibroblast Heterogeneity in Joint Homeostasis and Inflammation.

Knab K, Chambers D, Krönke G.

Front Med (Lausanne). 2022 Apr 25;9:862161. doi: 10.3389/fmed.2022.862161. eCollection 2022.

PMID: 35547214 Free PMC article. Review.

35.

Transmural intestinal fibrosis in men and mice.

Neufert C.

Gut. 2022 Jul;71(7):1242-1244. doi: 10.1136/gutjnl-2021-325522. Epub 2021 Nov 1.

PMID: 34725200 No abstract available.

36.

Response to contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells.

Iannacone M, Blériot C, Andreata F, Ficht X, Laura C, Garcia-Manteiga JM, Uderhardt S, Ginhoux F.

Immunity. 2022 Jul 12;55(7):1141-1142. doi: 10.1016/j.immuni.2022.06.012.

PMID: 35830819 No abstract available.

37.

Beyond Cancer: Regulation and Function of PD-L1 in Health and Immune-Related Diseases.

Beenen AC, Sauerer T, Schaft N, Dörrie J.

Int J Mol Sci. 2022 Aug 2;23(15):8599. doi: 10.3390/ijms23158599.

PMID: 35955729 Free PMC article. Review.

38.

Molecular Endoscopy for the Diagnosis and Therapeutic Monitoring of Colorectal Cancer.

Waldner MJ, Neurath MF.

Front Oncol. 2022 Feb 25;12:835256. doi: 10.3389/fonc.2022.835256. eCollection 2022.

PMID: 35280747 Free PMC article. Review.

39.

Generalisierte pustulöse Psoriasis: Überblick zum Status quo und Ergebnisse einer Diskussionsrunde.

Reich K, Augustin M, Gerdes S, Ghoreschi K, Kokolakis G, Mößner R, Mrowietz U, Navarini AA, Pinter A, Schäkel K, Staubach P, Sticherling M, Thaçi D, Wilsmann-Theis D.

J Dtsch Dermatol Ges. 2022 Jun;20(6):753-772. doi: 10.1111/ddg.14764_g.

PMID: 35711041 Review.

40.

Microbiota-Derived Propionate Modulates Megakaryopoiesis and Platelet Function.

Dürholz K, Schmid E, Frech M, Azizov V, Otterbein N, Lucas S, Rauh M, Schett G, Bruns H, Zaiss MM.

Front Immunol. 2022 Jul 8;13:908174. doi: 10.3389/fimmu.2022.908174. eCollection 2022.

PMID: 35880182 Free PMC article.

41.

Surface Design Options in Polymer- and Lipid-Based siRNA Nanoparticles Using Antibodies.

Gabel M, Knauss A, Fischer D, Neurath MF, Weigmann B.

Int J Mol Sci. 2022 Nov 11;23(22):13929. doi: 10.3390/ijms232213929.

PMID: 36430411 Free PMC article. Review.

42.

Post-COVID-19 Syndrome: Retinal Microcirculation as a Potential Marker for Chronic Fatigue.

Schlick S, Lucio M, Wallukat G, Bartsch A, Skornia A, Hoffmanns J, Szewczykowski C, Schröder T, Raith F, Rogge L, Heltmann F, Moritz M, Beitlich L, Schottenhamml J, Herrmann M, Harrer T, Ganslmayer M, Kruse FE, Lämmer R, Mardin C, Hohberger B.

Int J Mol Sci. 2022 Nov 8;23(22):13683. doi: 10.3390/ijms232213683.

PMID: 36430175 Free PMC article.

43.

Sequential interleukin-17/interleukin-23 inhibition in treatment-refractory psoriatic arthritis.

Simon D, Fagni F, Schett G.

Ann Rheum Dis. 2022 May 5:annrheumdis-2022-222415. doi: 10.1136/annrheumdis-2022-222415. Online ahead of print.

PMID: 35512847 No abstract available.

44.

Ileal and colonic Crohn's disease: Does location makes a difference in therapy efficacy?

Atreya R, Bojarski C, Kühl AA, Trajanoski Z, Neurath MF, Siegmund B.

Curr Res Pharmacol Drug Discov. 2022 Mar 19;3:100097. doi: 10.1016/j.crphar.2022.100097. eCollection 2022.

PMID: 35345820 Free PMC article. Review.

45.

Inflammatory Arthritis and Bone Metabolism Regulated by Type 2 Innate and Adaptive Immunity.

Omata Y, Frech M, Saito T, Schett G, Zaiss MM, Tanaka S.

Int J Mol Sci. 2022 Jan 20;23(3):1104. doi: 10.3390/ijms23031104.

PMID: 35163028 Free PMC article. Review.

46.

IL-23 Blockade in Anti-TNF Refractory IBD: From Mechanisms to Clinical Reality.

Atreya R, Neurath MF.

J Crohns Colitis. 2022 May 11;16(Supplement_2):ii54-ii63. doi: 10.1093/ecco-jcc/jjac007.

PMID: 35553662 Free PMC article. Review.

47.

The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective.

Lai X, Schmitz U, Vera J.

Adv Exp Med Biol. 2022;1385:1-22. doi: 10.1007/978-3-031-08356-3_1.

PMID: 36352209 Review.

48.

Bone marrow stroma cells promote induction of a chemoresistant and prognostic unfavorable S100A8/A9high AML cell subset.

Böttcher M, Panagiotidis K, Bruns H, Stumpf M, Völkl S, Geyh S, Dietel B, Schroeder T, Mackensen A, Mougiakakos D.

Blood Adv. 2022 Nov 8;6(21):5685-5697. doi: 10.1182/bloodadvances.2021005938.

PMID: 35390134 Free PMC article.

49.

How the Tumor Micromilieu Modulates the Recruitment and Activation of Colorectal Cancer-Infiltrating Lymphocytes.

Atreya I, Neurath MF.

Biomedicines. 2022 Nov 15;10(11):2940. doi: 10.3390/biomedicines10112940.

PMID: 36428508 Free PMC article. Review.

50.

Dynamic changes in O-GlcNAcylation regulate osteoclast differentiation and bone loss via nucleoporin 153.

Li YN, Chen CW, Trinh-Minh T, Zhu H, Matei AE, Györfi AH, Kuwert F, Hubel P, Ding X, Manh CT, Xu X, Liebel C, Fedorchenko V, Liang R, Huang K, Pfannstiel J, Huang MC, Lin NY, Ramming A, Schett G, Distler JHW.

Bone Res. 2022 Jul 26;10(1):51. doi: 10.1038/s41413-022-00218-9.

PMID: 35879285 Free PMC article.

51.

[DGRh S2e guidelines : Diagnostic and treatment of adult-onset Still's disease (AOSD)].

Vordenbäumen S, Feist E, Rech J, Fleck M, Blank N, Haas JP, Kötter I, Krusche M, Chehab G, Hoyer B, Kiltz U, Fell D, Reiners J, Weseloh C, Schneider M, Braun J.

Z Rheumatol. 2022 Dec;81(Suppl 1):1-20. doi: 10.1007/s00393-022-01276-4. Epub 2022 Nov 11.

PMID: 36367577 Review. German. No abstract available.

52.

Generalized pustular psoriasis: overview of the status quo and results of a panel discussion.

Reich K, Augustin M, Gerdes S, Ghoreschi K, Kokolakis G, Mößner R, Mrowietz U, Navarini AA, Pinter A, Schäkel K, Staubach P, Sticherling M, Thaçi D, Wilsmann-Theis D.

J Dtsch Dermatol Ges. 2022 Jun;20(6):753-771. doi: 10.1111/ddg.14764. Epub 2022 Jun 8.

PMID: 35674482 Review.

53.

[Inflammatory bowel diseases - therapy update 2022].

Atreya R, Neurath MF.

Dtsch Med Wochenschr. 2022 Mar;147(6):295-300. doi: 10.1055/a-1585-4026. Epub 2022 Mar 15.

PMID: 35291033 German.

54.

Rheumatoid arthritis and osteoimmunology: The adverse impact of a deregulated immune system on bone metabolism.

Andreev D, Kachler K, Schett G, Bozec A.

Bone. 2022 Sep;162:116468. doi: 10.1016/j.bone.2022.116468. Epub 2022 Jun 8.

PMID: 35688359 Review.

55.

Melanoma 2.0. Skin cancer as a paradigm for emerging diagnostic technologies, computational modelling and artificial intelligence.

Vera J, Lai X, Baur A, Erdmann M, Gupta S, Guttà C, Heinzerling L, Heppt MV, Kazmierczak PM, Kunz M, Lischer C, Pützer BM, Rehm M, Ostalecki C, Retzlaff J, Witt S, Wolkenhauer O, Berking C.

Brief Bioinform. 2022 Nov 19;23(6):bbac433. doi: 10.1093/bib/bbac433.

PMID: 36252807 Review.

56.

Wearables for Measuring the Physical Activity and Sedentary Behavior of Patients With Axial Spondyloarthritis: Systematic Review.

Soulard J, Carlin T, Knitza J, Vuillerme N.

JMIR Mhealth Uhealth. 2022 Aug 22;10(8):e34734. doi: 10.2196/34734.

PMID: 35994315 Free PMC article. Review.

57.

Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction.

Dölling M, Eckstein M, Singh J, Schauer C, Schoen J, Shan X, Bozec A, Knopf J, Schett G, Muñoz LE, Herrmann M.

Front Immunol. 2022 Feb 11;13:726153. doi: 10.3389/fimmu.2022.726153. eCollection 2022.

PMID: 35222361 Free PMC article.

58.

Efficacy and drug persistence of baricitinib monotherapy is similar to combination therapy in patients with active RA: a prospective observational study.

Bayat S, Tascilar K, Bohr D, Krönke G, Simon D, Knitza J, Hartmann F, Schett G, Kleyer A.

RMD Open. 2022 Nov;8(2):e002674. doi: 10.1136/rmdopen-2022-002674.

PMID: 36410777 Free PMC article.

59.

[Guideline report on the DGRh S2e guidelines on diagnostics and treatment of adult-onset Still's disease (AOSD)].

Vordenbäumen S, Feist E, Rech J, Fleck M, Blank N, Haas JP, Kötter I, Krusche M, Chehab G, Hoyer B, Kiltz U, Fell D, Reiners J, Weseloh C, Schneider M, Braun J.

Z Rheumatol. 2022 Dec;81(Suppl 1):21-27. doi: 10.1007/s00393-022-01277-3. Epub 2022 Nov 11.

PMID: 36367576 Review. German. No abstract available.

60.

[Case report: persistent fever after SARS-CoV-2 infection].

Kliem T, Strobel D, Heinke F, Pavel M, Neurath MF, Neufert C.

Inn Med (Heidelb). 2022 Jun;63(6):662-665. doi: 10.1007/s00108-022-01315-x. Epub 2022 Mar 17.

PMID: 35301546 Free PMC article. German.

61.

PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells.

Gerlach K, Popp V, Wirtz S, Al-Saifi R, Gonzalez Acera M, Atreya R, Dregelies T, Vieth M, Fichtner-Feigl S, McKenzie ANJ, Rosenbauer F, Weigmann B, Neurath MF.

J Crohns Colitis. 2022 Dec 5;16(12):1893-1910. doi: 10.1093/ecco-jcc/jjac097.

PMID: 35793807 Free PMC article.

62.

The Memory T Cell "Communication Web" in Context with Gastrointestinal Disorders-How Memory T Cells Affect Their Surroundings and How They Are Influenced by It.

Knauss A, Gabel M, Neurath MF, Weigmann B.

Cells. 2022 Sep 6;11(18):2780. doi: 10.3390/cells11182780.

PMID: 36139354 Free PMC article. Review.

63.

Induction of Ocular Surface Inflammation and Collection of Involved Tissues.

Singh J, Shan X, Mahajan A, Herrmann M, Schauer C, Knopf J, Muñoz LE.

J Vis Exp. 2022 Aug 4;(186). doi: 10.3791/63890.

PMID: 35993744

64.

Comparable neutralisation evasion of SARS-CoV-2 omicron subvariants BA.1, BA.2, and BA.3.

Arora P, Zhang L, Rocha C, Sidarovich A, Kempf A, Schulz S, Cossmann A, Manger B, Baier E, Tampe B, Moerer O, Dickel S, Dopfer-Jablonka A, Jäck HM, Behrens GMN, Winkler MS, Pöhlmann S, Hoffmann M.

Lancet Infect Dis. 2022 Jun;22(6):766-767. doi: 10.1016/S1473-3099(22)00224-9. Epub 2022 Apr 12.

PMID: 35427493 Free PMC article. No abstract available.

65.

Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets.

Becker E, Schweda A, Ullrich KA, Voskens C, Atreya R, Müller TM, Atreya I, Neurath MF, Zundler S.

Clin Transl Gastroenterol. 2022 Jun 1;13(6):e00494. doi: 10.14309/ctg.0000000000000494.

PMID: 35575178 Free PMC article.

66.

A disease network-based deep learning approach for characterizing melanoma.

Lai X, Zhou J, Wessely A, Heppt M, Maier A, Berking C, Vera J, Zhang L.

Int J Cancer. 2022 Mar 15;150(6):1029-1044. doi: 10.1002/ijc.33860. Epub 2021 Nov 17.

PMID: 34716589

67.

Is non-invasive Cytosponge the holy grail for Barrett's neoplasia?

Vieth M, Neurath MF.

Lancet Oncol. 2022 Feb;23(2):190-191. doi: 10.1016/S1470-2045(21)00755-5. Epub 2022 Jan 11.

PMID: 35030334 No abstract available.

68.

Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses.

Frech M, Omata Y, Schmalzl A, Wirtz S, Taher L, Schett G, Zaiss MM, Sarter K.

Front Immunol. 2022 Jan 25;13:757436. doi: 10.3389/fimmu.2022.757436. eCollection 2022.

PMID: 35145516 Free PMC article.

69.

Etrolizumab-s Does Not Induce Residual Trafficking of Regulatory T Cells.

Schweda A, Becker E, Wiendl M, Atreya R, Atreya I, Müller TM, Neurath MF, Zundler S.

Inflamm Bowel Dis. 2022 Nov 2;28(11):1746-1755. doi: 10.1093/ibd/izac137.

PMID: 35815779

70.

Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease.

Simon D, Tascilar K, Fagni F, Schmidt K, Krönke G, Kleyer A, Ramming A, Schoenau V, Bohr D, Knitza J, Harrer T, Manger K, Manger B, Schett G.

Ann Rheum Dis. 2022 Jul;81(7):1023-1027. doi: 10.1136/annrheumdis-2021-221554. Epub 2021 Nov 24.

PMID: 34819271

71.

Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity.

Reitinger C, Ipsen-Escobedo A, Hornung C, Heger L, Dudziak D, Lux A, Nimmerjahn F.

Front Immunol. 2022 Sep 29;13:970290. doi: 10.3389/fimmu.2022.970290. eCollection 2022.

PMID: 36248847 Free PMC article.

72.

NET Formation in Systemic Lupus Erythematosus: Changes during the COVID-19 Pandemic.

Knopf J, Sjöwall J, Frodlund M, Hinkula J, Herrmann M, Sjöwall C.

Cells. 2022 Aug 23;11(17):2619. doi: 10.3390/cells11172619.

PMID: 36078028 Free PMC article.

73.

Small but powerful: will nanoparticles be the future state-of-the-art therapy for IBD?

Lechner K, Zeeshan M, Noack M, Ali H, Neurath MF, Weigmann B.

Expert Opin Drug Deliv. 2022 Mar;19(3):235-245. doi: 10.1080/17425247.2022.2043847. Epub 2022 Mar 3.

PMID: 35184617

74.

Induction of microRNA-124 as a novel therapeutic concept in ulcerative colitis.

Atreya R, Neurath MF.

Lancet Gastroenterol Hepatol. 2022 Nov;7(11):977-978. doi: 10.1016/S2468-1253(22)00249-7. Epub 2022 Sep 6.

PMID: 36075248 No abstract available.

75.

Case report: Patient specific combination of surgery and immunotherapy in advanced squamous cell carcinoma of the head and neck - a case series and review of literature.

Olmos M, Lutz R, Büntemeyer TO, Glajzer J, Nobis CP, Ries J, Möst T, Eckstein M, Hecht M, Gostian AO, Erdmann M, Foerster Y, Kesting M, Weber M.

Front Immunol. 2022 Oct 27;13:970823. doi: 10.3389/fimmu.2022.970823. eCollection 2022.

PMID: 36389668 Free PMC article. Review.

76.

SMYD2 targets RIPK1 and restricts TNF-induced apoptosis and necroptosis to support colon tumor growth.

Yu YQ, Thonn V, Patankar JV, Thoma OM, Waldner M, Zielinska M, Bao LL, Gonzalez-Acera M, Wallmüller S, Engel FB, Stürzl M, Neurath MF, Liebing E, Becker C.

Cell Death Dis. 2022 Jan 12;13(1):52. doi: 10.1038/s41419-021-04483-0.

PMID: 35022391 Free PMC article.

77.

IgA Complexes Induce Neutrophil Extracellular Trap Formation More Potently Than IgG Complexes.

Gimpel AK, Maccataio A, Unterweger H, Sokolova MV, Schett G, Steffen U.

Front Immunol. 2022 Jan 13;12:761816. doi: 10.3389/fimmu.2021.761816. eCollection 2021.

PMID: 35095840 Free PMC article.

78.

STAT1 coordinates intestinal epithelial cell death during gastrointestinal infection upstream of Caspase-8.

Stolzer I, Schickedanz L, Chiriac MT, López-Posadas R, Grassl GA, Mattner J, Wirtz S, Winner B, Neurath MF, Günther C.

Mucosal Immunol. 2022 Jan;15(1):130-142. doi: 10.1038/s41385-021-00450-2. Epub 2021 Sep 8.

PMID: 34497340 Free PMC article.

79.

Epidermotropism of inflammatory cells differentiates pyoderma gangrenosum from venous leg ulcers.

Ronicke M, Baur A, Kirr M, Erdmann M, Erfurt-Berge C, Ostalecki C.

J Dtsch Dermatol Ges. 2022 May;20(5):619-627. doi: 10.1111/ddg.14708. Epub 2022 Apr 29.

PMID: 35487858

80.

A Pleomorphic Puzzle: Heterogeneous Pulmonary Vascular Occlusions in Patients with COVID-19.

Singh J, Herrmann I, Mahajan A, Schauer C, Shan X, Hartmann A, Rieker RJ, Evert K, Falkeis C, Naschberger E, von Stillfried S, Boor P, Muñoz LE, Schett G, Herrmann M, Knopf J.

Int J Mol Sci. 2022 Dec 1;23(23):15126. doi: 10.3390/ijms232315126.

PMID: 36499449 Free PMC article.

81.

Estrogen-mediated downregulation of HIF-1α signaling in B lymphocytes influences postmenopausal bone loss.

Meng X, Lin Z, Cao S, Janowska I, Sonomoto K, Andreev D, Katharina K, Wen J, Knaup KX, Wiesener MS, Krönke G, Rizzi M, Schett G, Bozec A.

Bone Res. 2022 Feb 17;10(1):15. doi: 10.1038/s41413-022-00189-x.

PMID: 35177582 Free PMC article.

82.

Rare meets rarer: anti-synthetase syndrome in a patient with facio-scapulo-humeral muscular dystrophy.

Valor-Méndez L, Manger B, Winterholler M, Schett G, Türk M, Knitza J.

Rheumatology (Oxford). 2022 Nov 28;61(12):e368-e370. doi: 10.1093/rheumatology/keac328.

PMID: 35642862 No abstract available.

83.

Comparison of physician and artificial intelligence-based symptom checker diagnostic accuracy.

Gräf M, Knitza J, Leipe J, Krusche M, Welcker M, Kuhn S, Mucke J, Hueber AJ, Hornig J, Klemm P, Kleinert S, Aries P, Vuillerme N, Simon D, Kleyer A, Schett G, Callhoff J.

Rheumatol Int. 2022 Dec;42(12):2167-2176. doi: 10.1007/s00296-022-05202-4. Epub 2022 Sep 10.

PMID: 36087130 Free PMC article.

84.

SMYD2 Inhibition Downregulates TMPRSS2 and Decreases SARS-CoV-2 Infection in Human Intestinal and Airway Epithelial Cells.

Yu YQ, Herrmann A, Thonn V, Cordsmeier A, Neurath MF, Ensser A, Becker C.

Cells. 2022 Apr 8;11(8):1262. doi: 10.3390/cells11081262.

PMID: 35455942 Free PMC article.

85.

Concise report: a minimal-invasive method to retrieve and identify entheseal tissue from psoriatic arthritis patients.

Pachowsky ML, Raimondo MG, Xu C, Rauber S, Tascilar K, Labinsky H, Vogg M, Aziz Saad MS, Simon D, Rech J, Soare A, Braeuer L, Kleyer A, Schett G, Ramming A.

Ann Rheum Dis. 2022 Aug;81(8):1131-1135. doi: 10.1136/annrheumdis-2021-222061. Epub 2022 Apr 22.

PMID: 35459697

86.

Lymph node and pulmonary tuberculosis during upadacitinib treatment in a psoriatic arthritis patient.

Valor-Méndez L, Manger B, Wacker J, Kleyer A, Schett G.

Rheumatol Adv Pract. 2022 May 13;6(2):rkac032. doi: 10.1093/rap/rkac032. eCollection 2022.

PMID: 35601270 Free PMC article. No abstract available.

87.

Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells.

Lanfer J, Kaindl J, Krumm L, Gonzalez Acera M, Neurath M, Regensburger M, Krach F, Winner B.

Int J Mol Sci. 2022 Apr 20;23(9):4526. doi: 10.3390/ijms23094526.

PMID: 35562917 Free PMC article.

88.

Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis-Associated Cancer in Mice.

Heichler C, Schmied A, Enderle K, Scheibe K, Murawska M, Schmid B, Waldner MJ, Neurath MF, Neufert C.

Cancers (Basel). 2022 Mar 14;14(6):1472. doi: 10.3390/cancers14061472.

PMID: 35326623 Free PMC article.

89.

Machine learning-based improvement of an online rheumatology referral and triage system.

Knitza J, Janousek L, Kluge F, von der Decken CB, Kleinert S, Vorbrüggen W, Kleyer A, Simon D, Hueber AJ, Muehlensiepen F, Vuillerme N, Schett G, Eskofier BM, Welcker M, Bartz-Bazzanella P.

Front Med (Lausanne). 2022 Jul 22;9:954056. doi: 10.3389/fmed.2022.954056. eCollection 2022.

PMID: 35935756 Free PMC article.

90.

IgA anti-citrullinated protein antibodies are associated with flares during DMARD tapering in rheumatoid arthritis.

Sokolova MV, Hagen M, Bang H, Schett G, Rech J, Steffen U; RETRO study group.

Rheumatology (Oxford). 2022 May 5;61(5):2124-2131. doi: 10.1093/rheumatology/keab585.

PMID: 34508547

91.

Angiotensin AT2 Receptor Stimulation Alleviates Collagen-Induced Arthritis by Upregulation of Regulatory T Cell Numbers.

Sehnert B, Valero-Esquitino V, Schett G, Unger T, Steckelings UM, Voll RE.

Front Immunol. 2022 Jul 8;13:921488. doi: 10.3389/fimmu.2022.921488. eCollection 2022.

PMID: 35874732 Free PMC article.

92.

Patient's Perception of Digital Symptom Assessment Technologies in Rheumatology: Results From a Multicentre Study.

Knitza J, Muehlensiepen F, Ignatyev Y, Fuchs F, Mohn J, Simon D, Kleyer A, Fagni F, Boeltz S, Morf H, Bergmann C, Labinsky H, Vorbrüggen W, Ramming A, Distler JHW, Bartz-Bazzanella P, Vuillerme N, Schett G, Welcker M, Hueber AJ.

Front Public Health. 2022 Feb 22;10:844669. doi: 10.3389/fpubh.2022.844669. eCollection 2022.

PMID: 35273944 Free PMC article. Clinical Trial.

93.

Treatment of refractory hypocomplementaemic urticarial vasculitis syndrome progressing to systemic lupus erythematosus with belimumab.

Valor-Méndez L, Schett G, Manger B.

Clin Exp Rheumatol. 2022 May;40(4):854-855. doi: 10.55563/clinexprheumatol/m9dexe. Epub 2021 Nov 17.

PMID: 34796852 No abstract available.

94.

Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging.

Kreiss L, Thoma OM, Lemire S, Lechner K, Carlé B, Dilipkumar A, Kunert T, Scheibe K, Heichler C, Merten AL, Weigmann B, Neufert C, Hildner K, Vieth M, Neurath MF, Friedrich O, Schürmann S, Waldner MJ.

Inflamm Bowel Dis. 2022 Nov 2;28(11):1637-1646. doi: 10.1093/ibd/izac114.

PMID: 35699622 Free PMC article.

95.

Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis.

Folle L, Bayat S, Kleyer A, Fagni F, Kapsner LA, Schlereth M, Meinderink T, Breininger K, Tascilar K, Krönke G, Uder M, Sticherling M, Bickelhaupt S, Schett G, Maier A, Roemer F, Simon D.

Rheumatology (Oxford). 2022 Nov 28;61(12):4945-4951. doi: 10.1093/rheumatology/keac197.

PMID: 35333316

96.

Calibration by differentiation - Self-supervised calibration for X-ray microscopy using a differentiable cone-beam reconstruction operator.

Thies M, Wagner F, Huang Y, Gu M, Kling L, Pechmann S, Aust O, Grüneboom A, Schett G, Christiansen S, Maier A.

J Microsc. 2022 Aug;287(2):81-92. doi: 10.1111/jmi.13125. Epub 2022 Jun 17.

PMID: 35638174

97.

Targeting of fibroblast activation protein in rheumatoid arthritis patients: imaging and ex vivo photodynamic therapy.

Dorst DN, Rijpkema M, Buitinga M, Walgreen B, Helsen MMA, Brennan E, Klein C, Laverman P, Ramming A, Schmidkonz C, Kuwert T, Schett G, van der Kraan PM, Gotthardt M, Koenders MI.

Rheumatology (Oxford). 2022 Jul 6;61(7):2999-3009. doi: 10.1093/rheumatology/keab664.

PMID: 34450633 Free PMC article.

98.

Real-World Data for Lenvatinib in Hepatocellular Carcinoma (ELEVATOR): A Retrospective Multicenter Study.

Welland S, Leyh C, Finkelmeier F, Jefremow A, Shmanko K, Gonzalez-Carmona MA, Kandulski A, Jeliazkova P, Best J, Fründt TW, Djanani A, Pangerl M, Maieron A, Greil R, Fricke C, Sookthai D, Günther R, Schmiderer A, Wege H, Venerito M, Ehmer U, Müller M, Strassburg CP, Weinmann A, Siebler J, Waidmann O, Lange CM, Saborowski A, Vogel A.

Liver Cancer. 2022 Jan 14;11(3):219-232. doi: 10.1159/000521746. eCollection 2022 Jun.

PMID: 35949288 Free PMC article.

99.

Association of Structural Entheseal Lesions With an Increased Risk of Progression From Psoriasis to Psoriatic Arthritis.

Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova MV, Zekovic A, Hueber AJ, Rech J, Schuster L, Engel K, Sticherling M, Schett G.

Arthritis Rheumatol. 2022 Feb;74(2):253-262. doi: 10.1002/art.41239. Epub 2021 Dec 30.

PMID: 32103639

100.

Rheumatoid arthritis, as a clinical disease, but not rheumatoid arthritis-associated autoimmunity, is linked to cardiovascular events.

Gouze H, Aegerter P, Said-Nahal R, Zins M, Goldberg M, Morelle G, Schett G, Breban M, D'Agostino MA.

Arthritis Res Ther. 2022 Feb 24;24(1):56. doi: 10.1186/s13075-022-02722-z.

PMID: 35209936 Free PMC article.

101.

Spontaneous regression rates of actinic keratosis: a systematic review and pooled analysis of randomized controlled trials.

Steeb T, Petzold A, Hornung A, Wessely A, Berking C, Heppt MV.

Sci Rep. 2022 Apr 7;12(1):5884. doi: 10.1038/s41598-022-09722-8.

PMID: 35393452 Free PMC article.

102.

Cluster analysis in early axial spondyloarthritis predicts poor outcome in the presence of peripheral articular manifestations.

Costantino F, Aegerter P, Schett G, De Craemer AS, Molto A, Van den Bosch F, Elewaut D, Breban M, D'Agostino MA.

Rheumatology (Oxford). 2022 Aug 3;61(8):3289-3298. doi: 10.1093/rheumatology/keab873.

PMID: 34864930 Clinical Trial.

103.

Multispectral optoacoustic tomography for the non-invasive identification of patients with severe anemia in vivo.

Ganzleben I, Klett D, Hartz W, Götzfried L, Vitali F, Neurath MF, Waldner MJ.

Photoacoustics. 2022 Oct 12;28:100414. doi: 10.1016/j.pacs.2022.100414. eCollection 2022 Dec.

PMID: 36276233 Free PMC article.

104.

Decitabine-Mediated Upregulation of CSPG4 in Ovarian Carcinoma Cells Enables Targeting by CSPG4-Specific CAR-T Cells.

Harrer DC, Schenkel C, Berking C, Herr W, Abken H, Dörrie J, Schaft N.

Cancers (Basel). 2022 Oct 14;14(20):5033. doi: 10.3390/cancers14205033.

PMID: 36291817 Free PMC article.

105.

Digitally-supported patient-centered asynchronous outpatient follow-up in rheumatoid arthritis - an explorative qualitative study.

Stenzel R, Hadaschik K, May S, Grahammer M, Labinsky H, Welcker M, Hornig J, Bendzuck G, Elling-Audersch C, Erstling U, Korbanka PS, Vuillerme N, Heinze M, Krönke G, Schett G, Pecher AC, Krusche M, Mucke J, Knitza J, Muehlensiepen F.

BMC Health Serv Res. 2022 Oct 28;22(1):1297. doi: 10.1186/s12913-022-08619-6.

PMID: 36307779 Free PMC article. Clinical Trial.

106.

Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry.

Studenic P, Hensvold A, Kleyer A, van der Helm-van Mil A, Pratt AG, Sieghart D, Krönke G, Williams R, de Souza S, Karlfeldt S, Johannesson M, Krogh NS, Klareskog L, Catrina AI.

Front Med (Lausanne). 2022 Feb 22;9:824501. doi: 10.3389/fmed.2022.824501. eCollection 2022.

PMID: 35273981 Free PMC article.

107.

Cinematic rendering in rheumatic diseases-Photorealistic depiction of pathologies improves disease understanding for patients.

Pachowsky ML, Morf H, Simon D, Schönau V, Valor-Mendez L, Knitza J, Fagni F, Engel K, Uder M, Hueber A, Schmidkonz C, Schett G, Kleyer A.

Front Med (Lausanne). 2022 Aug 3;9:946106. doi: 10.3389/fmed.2022.946106. eCollection 2022.

PMID: 35991672 Free PMC article.

108.

The metabolic profile of reconstituting T-cells, NK-cells, and monocytes following autologous stem cell transplantation and its impact on outcome.

Richter S, Böttcher M, Völkl S, Mackensen A, Ullrich E, Jacobs B, Mougiakakos D.

Sci Rep. 2022 Jul 6;12(1):11406. doi: 10.1038/s41598-022-15136-3.

PMID: 35794135 Free PMC article.

109.

Efficacy and safety of guselkumab and adalimumab for pustulotic arthro-osteitis and their impact on peripheral blood immunophenotypes.

Ueno M, Miyagawa I, Miyazaki Y, Hanami K, Fukuyo S, Kubo S, Nakayamada S, Tanaka Y.

Arthritis Res Ther. 2022 Oct 27;24(1):240. doi: 10.1186/s13075-022-02934-3.

PMID: 36303202 Free PMC article.

110.

Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Impaired Retinal Microcirculation.

Szewczykowski C, Mardin C, Lucio M, Wallukat G, Hoffmanns J, Schröder T, Raith F, Rogge L, Heltmann F, Moritz M, Beitlich L, Schottenhamml J, Herrmann M, Harrer T, Ganslmayer M, Kruse FE, Kräter M, Guck J, Lämmer R, Zenkel M, Gießl A, Hohberger B.

Int J Mol Sci. 2022 Jun 29;23(13):7209. doi: 10.3390/ijms23137209.

PMID: 35806214 Free PMC article.

111.

At-home blood self-sampling in rheumatology: a qualitative study with patients and health care professionals.

Muehlensiepen F, May S, Zarbl J, Vogt E, Boy K, Heinze M, Boeltz S, Labinsky H, Bendzuck G, Korinth M, Elling-Audersch C, Vuillerme N, Schett G, Krönke G, Knitza J.

BMC Health Serv Res. 2022 Dec 2;22(1):1470. doi: 10.1186/s12913-022-08787-5.

PMID: 36461025 Free PMC article.

112.

Effects of casirivimab/imdevimab on systemic and mucosal immunity against SARS-CoV-2 in B-cell depleted patients with autoimmune rheumatic diseases refractory to vaccination.

Fagni F, Schmidt K, Bohr D, Valor-Méndez L, Hartmann F, Tascilar K, Manger K, Manger B, Kleyer A, Simon D, Schett G, Harrer T.

RMD Open. 2022 May;8(1):e002323. doi: 10.1136/rmdopen-2022-002323.

PMID: 35589333 Free PMC article. No abstract available.

113.

Higher serum levels of short-chain fatty acids are associated with non-progression to arthritis in individuals at increased risk of RA.

Martinsson K, Dürholz K, Schett G, Zaiss MM, Kastbom A.

Ann Rheum Dis. 2022 Mar;81(3):445-447. doi: 10.1136/annrheumdis-2021-221386. Epub 2021 Nov 24.

PMID: 34819270 Free PMC article. No abstract available.

114.

Three generations of suffering: cryopyrin-associated periodic syndrome with NLRP3 mutation in a family.

Wagner N, Manger B, Kittler J, Rech J, Sticherling M, Berking C, Kirchberger MC.

J Dtsch Dermatol Ges. 2022 Jan;20(1):110-112. doi: 10.1111/ddg.14650. Epub 2021 Dec 13.

PMID: 34904355 No abstract available.

115.

Residual homing of α4β7-expressing β1+PI16+ regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab.

Becker E, Dedden M, Gall C, Wiendl M, Ekici AB, Schulz-Kuhnt A, Schweda A, Voskens C, Hegazy A, Vitali F, Atreya R, Müller TM, Atreya I, Neurath MF, Zundler S.

Gut. 2022 Aug;71(8):1551-1566. doi: 10.1136/gutjnl-2021-324868. Epub 2021 Aug 30.

PMID: 34462337

116.

Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice.

Kraemer AN, Schäfer AL, Sprenger DTL, Sehnert B, Williams JP, Luo A, Riechert L, Al-Kayyal Q, Dumortier H, Fauny JD, Winter Z, Heim K, Hofmann M, Herrmann M, Heine G, Voll RE, Chevalier N.

Front Immunol. 2022 Nov 24;13:933191. doi: 10.3389/fimmu.2022.933191. eCollection 2022.

PMID: 36505422 Free PMC article.

117.

Comparative efficacy analysis identifies immune checkpoint blockade as a new survival benchmark in advanced cutaneous squamous cell carcinoma.

Petzold A, Steeb T, Wessely A, Schatton T, Berking C, Heppt MV.

Eur J Cancer. 2022 Jul;170:42-53. doi: 10.1016/j.ejca.2022.03.035. Epub 2022 May 17.

PMID: 35594611

118.

Humoral and Cellular Immune Responses to SARS-CoV-2 Infection and Vaccination in Autoimmune Disease Patients With B Cell Depletion.

Simon D, Tascilar K, Schmidt K, Manger B, Weckwerth L, Sokolova M, Bucci L, Fagni F, Manger K, Schuch F, Ronneberger M, Hueber A, Steffen U, Mielenz D, Herrmann M, Harrer T, Kleyer A, Krönke G, Schett G.

Arthritis Rheumatol. 2022 Jan;74(1):33-37. doi: 10.1002/art.41914. Epub 2021 Nov 23.

PMID: 34196506 Free PMC article.

119.

Remote self-collection of capillary blood using upper arm devices for autoantibody analysis in patients with immune-mediated inflammatory rheumatic diseases.

Zarbl J, Eimer E, Gigg C, Bendzuck G, Korinth M, Elling-Audersch C, Kleyer A, Simon D, Boeltz S, Krusche M, Mucke J, Muehlensiepen F, Vuillerme N, Krönke G, Schett G, Knitza J.

RMD Open. 2022 Sep;8(2):e002641. doi: 10.1136/rmdopen-2022-002641.

PMID: 36104118 Free PMC article.

120.

A One-Armed Phase I Dose Escalation Trial Design: Personalized Vaccination with IKKβ-Matured, RNA-Loaded Dendritic Cells for Metastatic Uveal Melanoma.

Koch EAT, Schaft N, Kummer M, Berking C, Schuler G, Hasumi K, Dörrie J, Schuler-Thurner B.

Front Immunol. 2022 Feb 4;13:785231. doi: 10.3389/fimmu.2022.785231. eCollection 2022.

PMID: 35185883 Free PMC article.

121.

Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization.

Lai X, Keller C, Santos G, Schaft N, Dörrie J, Vera J.

Front Cell Dev Biol. 2022 Feb 2;9:746359. doi: 10.3389/fcell.2021.746359. eCollection 2021.

PMID: 35186943 Free PMC article.

122.

Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study.

Knevel R, Knitza J, Hensvold A, Circiumaru A, Bruce T, Evans S, Maarseveen T, Maurits M, Beaart-van de Voorde L, Simon D, Kleyer A, Johannesson M, Schett G, Huizinga T, Svanteson S, Lindfors A, Klareskog L, Catrina A.

Front Med (Lausanne). 2022 Apr 25;9:774945. doi: 10.3389/fmed.2022.774945. eCollection 2022.

PMID: 35547229 Free PMC article.

123.

Patient Characteristics and Treatment Patterns in European Pediatric Patients with Psoriasis: A Real-World, Cross-Sectional Study.

Sticherling M, McPherson T, de Lucas Laguna R, Costanzo A, Reed C, Artime E, Robert C, Lucas J, Schuster C, Mahé E.

Dermatol Ther (Heidelb). 2022 Aug;12(8):1793-1808. doi: 10.1007/s13555-022-00761-7. Epub 2022 Jul 7.

PMID: 35797001 Free PMC article.

124.

Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial.

Knitza J, Tascilar K, Vuillerme N, Eimer E, Matusewicz P, Corte G, Schuster L, Aubourg T, Bendzuck G, Korinth M, Elling-Audersch C, Kleyer A, Boeltz S, Hueber AJ, Krönke G, Schett G, Simon D.

Arthritis Res Ther. 2022 May 25;24(1):125. doi: 10.1186/s13075-022-02809-7.

PMID: 35614488 Free PMC article. Clinical Trial.

125.

Dose-response relationship of in vivo ambulatory load and mechanosensitive cartilage biomarkers-The role of age, tissue health and inflammation: A study protocol.

Herger S, Vach W, Nüesch C, Liphardt AM, Egloff C, Mündermann A.

PLoS One. 2022 Aug 19;17(8):e0272694. doi: 10.1371/journal.pone.0272694. eCollection 2022.

PMID: 35984848 Free PMC article. Clinical Trial.

126.

Transcriptomes of MPO-Deficient Patients with Generalized Pustular Psoriasis Reveals Expansion of CD4+ Cytotoxic T Cells and an Involvement of the Complement System.

Haskamp S, Frey B, Becker I, Schulz-Kuhnt A, Atreya I, Berking C, Pauli D, Ekici AB, Berges J, Mößner R, Wilsmann-Theis D, Sticherling M, Uebe S, Kirchner P, Hüffmeier U.

J Invest Dermatol. 2022 Aug;142(8):2149-2158.e10. doi: 10.1016/j.jid.2021.12.021. Epub 2021 Dec 30.

PMID: 34973310

127.

Self-collection of capillary blood and saliva to determine COVID-19 vaccine immunogenicity in patients with immune-mediated inflammatory diseases and health professionals.

Schmetzer C, Vogt E, Stellar L, Godonou ET, Liphardt AM, Muehlensiepen F, Vuillerme N, Hueber AJ, Kleyer A, Krönke G, Schett G, Simon D, Knitza J.

Front Public Health. 2022 Oct 14;10:994770. doi: 10.3389/fpubh.2022.994770. eCollection 2022.

PMID: 36311633 Free PMC article.

128.

Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer.

Hecht M, Eckstein M, Rutzner S, von der Grün J, Illmer T, Klautke G, Laban S, Hautmann MG, Brunner TB, Tamaskovics B, Hinke A, Zhou JG, Frey B, Donaubauer AJ, Becker I, Semrau S, Hartmann A, Balermpas P, Budach W, Gaipl US, Iro H, Gostian AO, Fietkau R.

J Immunother Cancer. 2022 Jan;10(1):e003747. doi: 10.1136/jitc-2021-003747.

PMID: 35078923 Free PMC article. Clinical Trial.

129.

Gender equity in academic rheumatology, current status and potential for improvement: a cross-sectional study to inform an EULAR task force.

Ovseiko PV, Gossec L, Andreoli L, Kiltz U, van Mens L, Hassan N, van der Leeden M, Siddle HJ, Alunno A, McInnes IB, Damjanov NS, Apparailly F, Ospelt C, van der Horst-Bruinsma IE, Nikiphorou E, Druce KL, Szekanecz Z, Sepriano A, Avcin T, Bertsias G, Schett G, Keenan AM, Pololi LH, Coates LC.

RMD Open. 2022 Aug;8(2):e002518. doi: 10.1136/rmdopen-2022-002518.

PMID: 35940824 Free PMC article.

130.

Reply to the comment on "Accuracy and usability of a diagnostic decision support system in the diagnosis of three representative rheumatic diseases: a randomized controlled trial among medical students".

Knitza J, Hueber AJ.

Arthritis Res Ther. 2022 May 24;24(1):123. doi: 10.1186/s13075-022-02806-w.

PMID: 35610629 Free PMC article. Clinical Trial. No abstract available.

131.

Expression of inflammatory mediators in biofilm samples and clinical association in inflammatory bowel disease patients-a preliminary study.

Buchbender M, Fehlhofer J, Proff P, Möst T, Ries J, Hannig M, Neurath MF, Gund M, Atreya R, Kesting M.

Clin Oral Investig. 2022 Feb;26(2):1217-1228. doi: 10.1007/s00784-021-04093-2. Epub 2021 Aug 12.

PMID: 34383142 Free PMC article. Clinical Trial.

132.

Natural NADH and FAD Autofluorescence as Label-Free Biomarkers for Discriminating Subtypes and Functional States of Immune Cells.

Lemire S, Thoma OM, Kreiss L, Völkl S, Friedrich O, Neurath MF, Schürmann S, Waldner MJ.

Int J Mol Sci. 2022 Feb 20;23(4):2338. doi: 10.3390/ijms23042338.

PMID: 35216453 Free PMC article.

133.

Efficacy and safety of a mobile app intervention in patients with inflammatory arthritis: a prospective pilot study.

Fedkov D, Berghofen A, Weiss C, Peine C, Lang F, Knitza J, Kuhn S, Krämer BK, Leipe J.

Rheumatol Int. 2022 Dec;42(12):2177-2190. doi: 10.1007/s00296-022-05175-4. Epub 2022 Sep 16.

PMID: 36112186 Free PMC article.

134.

Influence of alectinib and crizotinib on ionizing radiation - in vitro analysis of ALK/ROS1-wildtype lung tissue cells.

Jost T, Schultz AK, Frey B, Vu J, Fietkau R, Distel LV, Hecht M.

Neoplasia. 2022 May;27:100780. doi: 10.1016/j.neo.2022.100780. Epub 2022 Mar 9.

PMID: 35278911 Free PMC article.

135.

Proteins from Modern and Ancient Wheat Cultivars: Impact on Immune Cells of Healthy Individuals and Patients with NCGS.

Dieterich W, Schuster C, Gundel P, Scherf KA, Pronin D, Geisslitz S, Börner A, Neurath MF, Zopf Y.

Nutrients. 2022 Oct 12;14(20):4257. doi: 10.3390/nu14204257.

PMID: 36296938 Free PMC article.

136.

Epidermotropie von Immunzellen unterscheidet Pyoderma gangraenosum vom Ulcus cruris venosum.

Ronicke M, Baur A, Kirr M, Erdmann M, Erfurt-Berge C, Ostalecki C.

J Dtsch Dermatol Ges. 2022 May;20(5):619-628. doi: 10.1111/ddg.14708_g.

PMID: 35578412

137.

Real-World Therapy with Pembrolizumab: Outcomes and Surrogate Endpoints for Predicting Survival in Advanced Melanoma Patients in Germany.

Mohr P, Scherrer E, Assaf C, Bender M, Berking C, Chandwani S, Eigentler T, Grimmelmann I, Gutzmer R, Haferkamp S, Hassel JC, Hauschild A, Herbst R, Jiang R, Kähler KC, Krepler C, Kreuter A, Leiter U, Loquai C, Meier F, Pföhler C, Rudolph A, Schadendorf D, Schiavone M, Schley G, Terheyden P, Ugurel S, Ulrich J, Utikal J, Weishaupt C, Welzel J, Weichenthal M.

Cancers (Basel). 2022 Apr 1;14(7):1804. doi: 10.3390/cancers14071804.

PMID: 35406577 Free PMC article.

138.

The Effect of Hyperthermia and Radiotherapy Sequence on Cancer Cell Death and the Immune Phenotype of Breast Cancer Cells.

Sengedorj A, Hader M, Heger L, Frey B, Dudziak D, Fietkau R, Ott OJ, Scheidegger S, Barba SM, Gaipl US, Rückert M.

Cancers (Basel). 2022 Apr 19;14(9):2050. doi: 10.3390/cancers14092050.

PMID: 35565180 Free PMC article.

139.

Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study.

Simon D, Tascilar K, Fagni F, Kleyer A, Krönke G, Meder C, Dietrich P, Orlemann T, Mößner J, Taubmann J, Mutlu MY, Knitza J, Kemenes S, Liphardt AM, Schönau V, Bohr D, Schuster L, Hartmann F, Minopoulou I, Leppkes M, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Hueber AJ, Manger K, Manger B, Atreya R, Berking C, Sticherling M, Neurath MF, Schett G.

Lancet Rheumatol. 2022 Sep;4(9):e614-e625. doi: 10.1016/S2665-9913(22)00191-6. Epub 2022 Aug 9.

PMID: 35966645 Free PMC article.

140.

Re-exposure with a TNF inhibitor bio-similar was well tolerated and led to sustained control of psoriatic arthritis after allergic reaction to the TNF inhibitor bio-originator.

Valor-Méndez L, Dorn C, Manger B, Schett G, Kleyer A.

Rheumatol Adv Pract. 2022 Oct 10;6(3):rkac079. doi: 10.1093/rap/rkac079. eCollection 2022.

PMID: 36268524 Free PMC article. No abstract available.

141.

Impact of off-label use regulations on patient care in dermatology - a prospective study of cost-coverage applications filed by tertiary dermatology clinics throughout Germany.

Werner RN, Pennitz A, Eisert L, Schmidle P, Zink A, Abraham S, Schäkel K, Wolff I, Goebeler M, Plange J, Sollfrank L, Zielbauer S, Koll P, Amschler K, Müller V, Nast A.

J Eur Acad Dermatol Venereol. 2022 Nov;36(11):2241-2249. doi: 10.1111/jdv.18357. Epub 2022 Jul 7.

PMID: 35737866

142.

Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns-How Neural Networks Can Tell Us Where to "Deep Dive" Clinically.

Folle L, Simon D, Tascilar K, Krönke G, Liphardt AM, Maier A, Schett G, Kleyer A.

Front Med (Lausanne). 2022 Mar 10;9:850552. doi: 10.3389/fmed.2022.850552. eCollection 2022.

PMID: 35360728 Free PMC article.

143.

Review and Analysis of German Mobile Apps for Inflammatory Bowel Disease Management Using the Mobile Application Rating Scale: Systematic Search in App Stores and Content Analysis.

Gerner M, Vuillerme N, Aubourg T, Messner EM, Terhorst Y, Hörmann V, Ganzleben I, Schenker H, Schett G, Atreya R, Neurath MF, Knitza J, Orlemann T.

JMIR Mhealth Uhealth. 2022 May 3;10(5):e31102. doi: 10.2196/31102.

PMID: 35503246 Free PMC article.

144.

Real-world evidence from the non-interventional, prospective, German multicentre PERSIST study of patients with psoriasis after 1 year of treatment with guselkumab.

Gerdes S, Asadullah K, Hoffmann M, Korge B, Mortazawi D, Wegner S, Personke Y, Gomez M, Sticherling M.

J Eur Acad Dermatol Venereol. 2022 Sep;36(9):1568-1577. doi: 10.1111/jdv.18218. Epub 2022 May 25.

PMID: 35569014

145.

Neutralizing monoclonal antibodies against SARS-CoV-2 for COVID-19 pneumonia in a rituximab treated patient with systemic sclerosis-A case report and literature review.

Yalcin Mutlu M, Taubmann J, Wacker J, Tascilar K, Fagni F, Gerner M, Klett D, Schett G, Manger B, Simon D.

Front Med (Lausanne). 2022 Aug 3;9:934169. doi: 10.3389/fmed.2022.934169. eCollection 2022.

PMID: 35991632 Free PMC article.

146.

A network medicine approach for identifying diagnostic and prognostic biomarkers and exploring drug repurposing in human cancer.

Zhang L, Fan S, Vera J, Lai X.

Comput Struct Biotechnol J. 2022 Nov 29;21:34-45. doi: 10.1016/j.csbj.2022.11.037. eCollection 2023.

PMID: 36514340 Free PMC article.