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Publikationen 2024

1.

L-arginine metabolism inhibits arthritis and inflammatory bone loss.

Cao S, Li Y, Song R, Meng X, Fuchs M, Liang C, Kachler K, Meng X, Wen J, Schlötzer-Schrehardt U, Taudte V, Gessner A, Kunz M, Schleicher U, Zaiss MM, Kastbom A, Chen X, Schett G, Bozec A.

Ann Rheum Dis. 2024 Jan 2;83(1):72-87. doi: 10.1136/ard-2022-223626.

PMID: 37775153 Free PMC article.

2.

Functional In Vivo Imaging of Macrophages.

Wegner A, Palmisano R, Uderhardt S.

Methods Mol Biol. 2024;2713:323-335. doi: 10.1007/978-1-0716-3437-0_22.

PMID: 37639133

3.

Dynamic Multiplex Tissue Imaging in Inflammation Research.

Uderhardt S, Neag G, Germain RN.

Annu Rev Pathol. 2024 Jan 24;19:43-67. doi: 10.1146/annurev-pathmechdis-070323-124158. Epub 2023 Sep 18.

PMID: 37722698 Review.

4.

Double-edged sword: Alcohol's effect on rheumatoid arthritis and beyond.

Hübner M, Zaiss MM, Azizov V.

Joint Bone Spine. 2024 Jan;91(1):105626. doi: 10.1016/j.jbspin.2023.105626. Epub 2023 Aug 4.

PMID: 37543136 No abstract available.

5.

Metabolic and molecular imaging in inflammatory arthritis.

Noversa de Sousa R, Tascilar K, Corte G, Atzinger A, Minopoulou I, Ohrndorf S, Waldner M, Schmidkonz C, Kuwert T, Knieling F, Kleyer A, Ramming A, Schett G, Simon D, Fagni F.

RMD Open. 2024 Feb 9;10(1):e003880. doi: 10.1136/rmdopen-2023-003880.

PMID: 38341194 Free PMC article. Review.

6.

The Proteomic Signature of Tissue Remodeling in Chronic Intestinal Inflammation.

Neurath MF.

Cell Mol Gastroenterol Hepatol. 2024 Feb 5:S2352-345X(24)00022-5. doi: 10.1016/j.jcmgh.2024.01.019. Online ahead of print.

PMID: 38331388 No abstract available.

7.

Identifying biomarkers and novel therapeutic targets in uveal melanoma.

Wessely A, Koch EAT, Vera J, Berking C, Heppt MV.

J Dtsch Dermatol Ges. 2024 Jan;22(1):29-32. doi: 10.1111/ddg.15225. Epub 2023 Oct 30.

PMID: 37902386 Review.

8.

Biomarkers for personalizing IBD therapy: The quest continues.

Atreya R, Neurath MF.

Clin Gastroenterol Hepatol. 2024 Feb 4:S1542-3565(24)00104-6. doi: 10.1016/j.cgh.2024.01.026. Online ahead of print.

PMID: 38320679 Review.

9.

Rescue therapy of antisynthetase syndrome with CD19-targeted CAR-T cells after failure of several B-cell depleting antibodies.

Taubmann J, Knitza J, Müller F, Völkl S, Aigner M, Kleyer A, Gary R, Kretschmann S, Boeltz S, Atzinger A, Kuwert T, Roemer F, Uder M, Mackensen A, Schett G.

Rheumatology (Oxford). 2024 Jan 4;63(1):e12-e14. doi: 10.1093/rheumatology/kead330.

PMID: 37432378 Free PMC article. No abstract available.

10.

IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.

Chiriac MT, Hracsko Z, Günther C, Gonzalez-Acera M, Atreya R, Stolzer I, Wittner L, Dressel A, Schickedanz L, Gamez-Belmonte R, Erkert L, Hundorfean G, Zundler S, Rath T, Vetrano S, Danese S, Sturm G, Trajanoski Z, Kühl AA, Siegmund B, Hartmann A, Wirtz S, Siebler J, Finotto S, Becker C, Neurath MF.

Gut. 2024 Jan 5;73(2):282-297. doi: 10.1136/gutjnl-2023-329628.

PMID: 37884352 Free PMC article.

11.

Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection.

Barmada A, Handfield LF, Godoy-Tena G, de la Calle-Fabregat C, Ciudad L, Arutyunyan A, Andrés-León E, Hoo R, Porter T, Oszlanczi A, Richardson L, Calero-Nieto FJ, Wilson NK, Marchese D, Sancho-Serra C, Carrillo J, Presas-Rodríguez S, Ramo-Tello C, Ruiz-Sanmartin A, Ferrer R, Ruiz-Rodriguez JC, Martínez-Gallo M, Munera-Campos M, Carrascosa JM, Göttgens B, Heyn H, Prigmore E, Casafont-Solé I, Solanich X, Sánchez-Cerrillo I, González-Álvaro I, Raimondo MG, Ramming A, Martin J, Martínez-Cáceres E, Ballestar E, Vento-Tormo R, Rodríguez-Ubreva J.

Eur J Immunol. 2024 Jan;54(1):e2350633. doi: 10.1002/eji.202350633. Epub 2023 Oct 20.

PMID: 37799110

12.

Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment.

Overbeek KA, Poulsen JL, Lanzillotta M, Vinge-Holmquist O, Macinga P, Demirci AF, Sindhunata DP, Backhus J, Algül H, Buijs J, Levy P, Kiriukova M, Goni E, Hollenbach M, Miksch RC, Kunovsky L, Vujasinovic M, Nikolic S, Dickerson L, Hirth M, Neurath MF, Zumblick M, Vila J, Jalal M, Beyer G, Frost F, Carrara S, Kala Z, Jabandziev P, Sisman G, Akyuz F, Capurso G, Falconi M, Arlt A, Vleggaar FP, Barresi L, Greenhalf B, Czakó L, Hegyi P, Hopper A, Nayar MK, Gress TM, Vitali F, Schneider A, Halloran CM, Trna J, Okhlobystin AV, Dagna L, Cahen DL, Bordin D, Rebours V, Mayerle J, Kahraman A, Rasch S, Culver E, Kleger A, Martínez-Moneo E, Røkke O, Hucl T, Olesen SS, Bruno MJ, Della-Torre E, Beuers U, Löhr JM, Rosendahl J; PrescrAIP Study Group.

Clin Gastroenterol Hepatol. 2024 Jan 5:S1542-3565(23)01042-X. doi: 10.1016/j.cgh.2023.12.010. Online ahead of print.

PMID: 38184096

13.

Transferrin receptor 2 mitigates periodontitis-driven alveolar bone loss.

Lösser L, Ledesma-Colunga MG, Andrés Sastre E, Scholtysek C, Hofbauer LC, Noack B, Baschant U, Rauner M.

J Cell Physiol. 2024 Feb;239(2):e31172. doi: 10.1002/jcp.31172. Epub 2024 Jan 12.

PMID: 38214117

14.

ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo.

Schulz-Kuhnt A, Rühle K, Javidmehr A, Döbrönti M, Biwank J, Knittel S, Neidlinger P, Leupold J, Liu LJ, Dedden M, Taudte RV, Gessner A, Fromm MF, Mielenz D, Kreiss L, Waldner MJ, Schürmann S, Friedrich O, Dietel B, López-Posadas R, Plattner C; TRR241 IBDome Consortium; Zundler S, Becker C, Atreya R, Neurath MF, Atreya I.

Gut. 2024 Jan 4:gutjnl-2023-330543. doi: 10.1136/gutjnl-2023-330543. Online ahead of print.

PMID: 38176897

15.

p21 Prevents the Exhaustion of CD4+ T Cells Within the Antitumor Immune Response Against Colorectal Cancer.

Thoma OM, Naschberger E, Kubánková M, Larafa I, Kramer V, Menchicchi B, Merkel S, Britzen-Laurent N, Jefremow A, Grützmann R, Koop K, Neufert C, Atreya R, Guck J, Stürzl M, Neurath MF, Waldner MJ.

Gastroenterology. 2024 Feb;166(2):284-297.e11. doi: 10.1053/j.gastro.2023.09.017. Epub 2023 Sep 19.

PMID: 37734420

16.

Clinical presentation and genetic variants in patients with autoinflammatory diseases: results from the German GARROD registry.

Blank N, Kötter I, Schmalzing M, Rech J, Krause K, Köhler B, Kaudewitz D, Nitschke M, Haas CS, Lorenz HM, Krusche M.

Rheumatol Int. 2024 Feb;44(2):263-271. doi: 10.1007/s00296-023-05443-x. Epub 2023 Sep 25.

PMID: 37747561 Free PMC article.

17.

Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients.

Krumm L, Pozner T, Zagha N, Coras R, Arnold P, Tsaktanis T, Scherpelz K, Davis MY, Kaindl J, Stolzer I, Süß P, Khundadze M, Hübner CA, Riemenschneider MJ, Baets J, Günther C, Jayadev S, Rothhammer V, Krach F, Winkler J, Winner B, Regensburger M.

Acta Neuropathol. 2024 Feb 2;147(1):28. doi: 10.1007/s00401-023-02675-w.

PMID: 38305941 Free PMC article.

18.

Blocking GPR15 counteracts integrin-dependent T cell gut homing in vivo.

Schramm S, Liu LJ, Saad M, Dietz L, Dedden M, Müller TM, Atreya I, Voskens CJ, Atreya R, Neurath MF, Zundler S.

J Crohns Colitis. 2024 Jan 18:jjae012. doi: 10.1093/ecco-jcc/jjae012. Online ahead of print.

PMID: 38243565

19.

DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis.

Willemsen JF, Wenskus J, Lenz M, Rhode H, Trochimiuk M, Appl B, Pagarol-Raluy L, Börnigen D, Bang C, Reinshagen K, Herrmann M, Elrod J, Boettcher M.

Front Immunol. 2024 Jan 8;14:1254838. doi: 10.3389/fimmu.2023.1254838. eCollection 2023.

PMID: 38259485 Free PMC article.

20.

Discrimination of pancreato-biliary cancer and pancreatitis patients by non-invasive liquid biopsy.

Hartwig C, Müller J, Klett H, Kouhestani D, Mittelstädt A, Anthuber A, David P, Brunner M, Jacobsen A, Glanz K, Swierzy I, Roßdeutsch L, Klösch B, Grützmann R, Wittenberger T, Sohn K, Weber GF.

Mol Cancer. 2024 Feb 2;23(1):28. doi: 10.1186/s12943-024-01943-x.

PMID: 38308296 Free PMC article.

21.

Etrolizumab-s fails to control E-Cadherin-dependent co-stimulation of highly activated cytotoxic T cells.

Wiendl M, Dedden M, Liu LJ, Schweda A, Paap EM, Ullrich KA, Hartmann L, Wieser L, Vitali F, Atreya I, Müller TM, Günther C, Atreya R, Neurath MF, Zundler S.

Nat Commun. 2024 Feb 3;15(1):1043. doi: 10.1038/s41467-024-45352-6.

PMID: 38310086 Free PMC article.

22.

Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity.

Hansen MS, Madsen K, Price M, Søe K, Omata Y, Zaiss MM, Gorvin CM, Frost M, Rauch A.

Bone Res. 2024 Jan 24;12(1):5. doi: 10.1038/s41413-023-00312-6.

PMID: 38263167 Free PMC article.

23.

Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase.

Andreev D, Kachler K, Liu M, Chen Z, Krishnacoumar B, Ringer M, Frey S, Krönke G, Voehringer D, Schett G, Bozec A.

Nat Commun. 2024 Feb 5;15(1):1067. doi: 10.1038/s41467-024-45261-8.

PMID: 38316791 Free PMC article.

24.

Innovative cellular therapies for autoimmune diseases: expert-based position statement and clinical practice recommendations from the EBMT practice harmonization and guidelines committee.

Greco R, Alexander T, Del Papa N, Müller F, Saccardi R, Sanchez-Guijo F, Schett G, Sharrack B, Snowden JA, Tarte K, Onida F, Sánchez-Ortega I, Burman J, Castilla Llorente C, Cervera R, Ciceri F, Doria A, Henes J, Lindsay J, Mackensen A, Muraro PA, Ricart E, Rovira M, Zuckerman T, Yakoub-Agha I, Farge D.

EClinicalMedicine. 2024 Feb 10;69:102476. doi: 10.1016/j.eclinm.2024.102476. eCollection 2024 Mar.

PMID: 38361991 Free PMC article. Review.

25.

Interplay between COVID-19 and Secukinumab treatment in Spondylarthritis patients during the omicron surge: a retrospective cohort study.

Wu T, Li Y, Huang D, Wu Y, Liang X, Cheng L, Liao Z, Xu F, Chen Y, Zhao J, Xia Z, Tan C, Liu Y, Herrmann M.

Autoimmunity. 2024 Dec;57(1):2281242. doi: 10.1080/08916934.2023.2281242. Epub 2023 Dec 13.

PMID: 38093504

26.

CCL19-positive lymph node stromal cells govern the onset of inflammatory arthritis via tropomyosin receptor kinase.

Schälter F, Azizov V, Frech M, Dürholz K, Schmid E, Hendel A, Sarfati I, Maeda Y, Sokolova M, Miyagawa I, Focke K, Sarter K, van Baarsen LGM, Krautwald S, Schett G, Zaiss MM.

Arthritis Rheumatol. 2024 Jan 25. doi: 10.1002/art.42807. Online ahead of print.

PMID: 38268500

27.

Stepwise asynchronous telehealth assessment of patients with suspected axial spondyloarthritis: results from a pilot study.

Hannah L, von Sophie R, Gabriella RM, Daniela B, Harriet M, Britta H, Felix S, Fabian P, Felix M, Katharina B, Sebastian K, Marc S, Nicolas V, Georg S, Andreas R, Johannes K.

Rheumatol Int. 2024 Jan;44(1):173-180. doi: 10.1007/s00296-023-05360-z. Epub 2023 Jun 14.

PMID: 37316631 Free PMC article.

28.

2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice.

Mandl P, D'Agostino MA, Navarro-Compán V, Geßl I, Sakellariou G, Abhishek A, Becce F, Dalbeth N, Ea HK, Filippucci E, Hammer HB, Iagnocco A, de Thurah A, Naredo E, Ottaviani S, Pascart T, Pérez-Ruiz F, Pitsillidou IA, Proft F, Rech J, Schmidt WA, Sconfienza LM, Terslev L, Wildner B, Zufferey P, Filippou G.

Ann Rheum Dis. 2024 Feb 6:ard-2023-224771. doi: 10.1136/ard-2023-224771. Online ahead of print.

PMID: 38320811

29.

Immobilization by 21 days of bed rest results in type II collagen degradation in healthy individuals.

Liphardt AM, Godonou ET, Dreiner M, Mündermann A, Tascilar K, Djalal N, Heer M, Schett G, Zaucke F, Niehoff A.

Osteoarthritis Cartilage. 2024 Feb;32(2):177-186. doi: 10.1016/j.joca.2023.11.007. Epub 2023 Nov 19.

PMID: 37989468

30.

The side effect registry immuno-oncology (SERIO) - A tool for systematic analysis of immunotherapy-induced side effects.

Ertl C, Ruf T, Mentzer D, Kong M, Kramer R, Bergwelt-Baildon MV, Subklewe M, Tomsitz D, Ascierto PA, Dummer R, Gogas H, Lebbé C, Long GV, McArthur G, Neilan TG, Ribas A, Robert C, Schadendorf D, Zimmer L, Eigentler T, Grabbe S, Forschner A, Kähler KC, Milani V, Pföhler C, Hassel J, Gutzmer R, Loquai C, Routy B, Furness AJS, Blank C, Wolchok JD, French LE, Hauschild A, Heinzerling L.

Eur J Cancer. 2024 Mar;199:113505. doi: 10.1016/j.ejca.2023.113505. Epub 2023 Dec 23.

PMID: 38262306

31.

Internal vascular anatomy of the human lacrimal gland: A protocol based on cadaver dissection and three-dimensional micro-computed tomography.

Singh S, Chopra P, Necker F, Scholz M, Liphardt AM, Schuster L, Paulsen F, Bräuer L.

Ann Anat. 2024 Feb;252:152207. doi: 10.1016/j.aanat.2023.152207. Epub 2023 Dec 29.

PMID: 38159615

32.

Long-term safety and effectiveness of canakinumab in patients with monogenic autoinflammatory diseases: results from the interim analysis of the RELIANCE registry.

Kuemmerle-Deschner JB, Kallinich T, Henes J, Kortus-Götze B, Oommen PT, Rech J, Krickau T, Weller-Heinemann F, Horneff G, Janda A, Foeldvari I, Schuetz C, Dressler F, Borte M, Hufnagel M, Meier F, Fiene M, Andreica I, Weber-Arden J, Blank N.

RMD Open. 2024 Feb 15;10(1):e003890. doi: 10.1136/rmdopen-2023-003890.

PMID: 38360038 Free PMC article.

33.

Abatacept inhibits inflammation and onset of rheumatoid arthritis in individuals at high risk (ARIAA): a randomised, international, multicentre, double-blind, placebo-controlled trial.

Rech J, Tascilar K, Hagen M, Kleyer A, Manger B, Schoenau V, Hueber AJ, Kleinert S, Baraliakos X, Braun J, Kiltz U, Fleck M, Rubbert-Roth A, Kofler DM, Behrens F, Feuchtenberger M, Zaenker M, Voll R, Venhoff N, Thiel J, Glaser C, Feist E, Burmester GR, Karberg K, Strunk J, Cañete JD, Senolt L, Filkova M, Naredo E, Largo R, Krönke G, D'Agostino MA, Østergaard M, Schett G.

Lancet. 2024 Feb 13:S0140-6736(23)02650-8. doi: 10.1016/S0140-6736(23)02650-8. Online ahead of print.

PMID: 38364841